{"id":10449,"date":"2025-03-07T11:16:39","date_gmt":"2025-03-07T10:16:39","guid":{"rendered":"https:\/\/www.tempco.it\/blog\/?p=10449"},"modified":"2025-12-03T15:44:58","modified_gmt":"2025-12-03T14:44:58","slug":"chiller-at-30-c-for-high-precision-cooling-in-pharma-production","status":"publish","type":"post","link":"https:\/\/www.tempco.it\/blog\/en\/10449\/chiller-at-30-c-for-high-precision-cooling-in-pharma-production\/","title":{"rendered":"Chiller at -30\u00b0 C for high precision cooling in pharma production"},"content":{"rendered":"<p>In the <a href=\"https:\/\/www.tempco.it\/blog\/en\/8156\/monofluid-thermoregulation-in-pharma-group-for-api-production\/\"><strong>pharmaceutical industry<\/strong><\/a>, precision cooling is essential to <strong>ensure the stability of chemical reactions<\/strong> and the quality of the finished product. <strong>Tempco<\/strong> recently supplied <strong>two water-cooled <a href=\"https:\/\/en.tempco.it\/solutions-en\/chillers\/\" target=\"_blank\" rel=\"noopener\">chillers<\/a><\/strong>, designed to operate with a <strong>water\/glycol solution at -30\u00b0C<\/strong>, to cool reactors in a new pharmaceutical production line.<\/p>\n<p>This supply, completed at the end of last year and completely commissioned in January with a positive on-site test, stood out for two key factors:<\/p>\n<ul>\n<li><strong>Performance and reliability<\/strong>: system designed to ensure 24\/7 operational continuity.<\/li>\n<li><strong>Reduced delivery times<\/strong>: design, construction and testing completed on time, allowing the customer to start production without delays.<\/li>\n<\/ul>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-10439 \" src=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma.jpg\" alt=\"Image showing a Tempco chiller capable of reaching cooling temperatures of -30\u00b0C for the thermal control required to ensure stable reactions in the pharmaceutical industry.\" width=\"611\" height=\"458\" srcset=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma.jpg 1361w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-300x225.jpg 300w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-1024x767.jpg 1024w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-768x576.jpg 768w\" sizes=\"(max-width: 611px) 100vw, 611px\" \/><\/p>\n<p>Below are the <strong>technical characteristics of the chillers<\/strong> supplied:<\/p>\n<p>\u2022 Process fluid: 50% inhibited water\/monoethylene glycol mixture<br \/>\n\u2022 Operating temperature: -30\u00b0C<br \/>\n\u2022 Cooling capacity: 75 kW per unit<br \/>\n\u2022 Water condensation with <a href=\"https:\/\/en.tempco.it\/solutions-en\/heat-exchangers\/\" target=\"_blank\" rel=\"noopener\">plate heat exchangers<\/a><br \/>\n\u2022 Indoor installation, in a safe area of \u200b\u200bthe production site<br \/>\n\u2022 Power supply voltage: 400V &#8211; 3F &#8211; 50Hz<\/p>\n<p>The chillers have an <strong>integrated hydraulic circuit<\/strong>, and each unit is supplied complete with: <strong>circulation pump<\/strong>, with a prevalence of 2\u00f72.5 bar, ensuring a stable and constant flow to the reactors; <strong>accumulation tank<\/strong>, to optimize thermal management and reduce temperature fluctuations; <strong>thermostatic valves<\/strong>, for precise control of the refrigeration regulation; <strong>AISI 304 stainless steel tanks and pipes<\/strong>, with stainless steel sheet insulation and cladding, to ensure durability and optimal thermal insulation.<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-10441 \" src=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-industria-farmaceutica.jpg\" alt=\"Image showing a unit with integrated hydraulic circuit and a Tempco chiller at -30\u00b0C for the thermal control required to ensure stable reactions in the pharmaceutical industry.\" width=\"610\" height=\"343\" srcset=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-industria-farmaceutica.jpg 1361w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-industria-farmaceutica-300x169.jpg 300w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-industria-farmaceutica-1024x576.jpg 1024w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-industria-farmaceutica-768x432.jpg 768w\" sizes=\"(max-width: 610px) 100vw, 610px\" \/><\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-10443 \" src=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-processi-farmaceutici.jpg\" alt=\"Image showing the details of a unit with integrated hydraulic circuit and a Tempco chiller at -30\u00b0C for the thermal control required to ensure stable reactions in the pharmaceutical industry.\" width=\"610\" height=\"815\" srcset=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-processi-farmaceutici.jpg 1020w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-processi-farmaceutici-225x300.jpg 225w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-processi-farmaceutici-767x1024.jpg 767w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-processi-farmaceutici-768x1025.jpg 768w\" sizes=\"(max-width: 610px) 100vw, 610px\" \/><\/p>\n<p>Finally, there are several advantages ensured by this system created for the customer:<\/p>\n<ul>\n<li><strong>Maximum energy efficiency<\/strong> &#8211; thanks to water condensation and the use of high-efficiency plate exchangers.<\/li>\n<li><strong>Precision in temperature control<\/strong> &#8211; essential for the stability of pharmaceutical chemical processes.<\/li>\n<li><strong>Operational reliability<\/strong> &#8211; designed to operate continuously without interruptions.<\/li>\n<li><strong>Plug &amp; play installation<\/strong> &#8211; thanks to the complete integration of the hydraulic part, the system was immediately put into production after testing.<\/li>\n<\/ul>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter wp-image-10445 \" src=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-installazione.jpg\" alt=\"Image showing an installation of a unit with a Tempco chiller for cooling to -30\u00b0C for the thermal control required to ensure stable reactions in the pharmaceutical industry.\" width=\"611\" height=\"458\" srcset=\"https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-installazione.jpg 1361w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-installazione-300x225.jpg 300w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-installazione-1024x767.jpg 1024w, https:\/\/www.tempco.it\/blog\/wp-content\/uploads\/2025\/03\/Tempco-chiller-30-C-controllo-termico-pharma-installazione-768x576.jpg 768w\" sizes=\"(max-width: 611px) 100vw, 611px\" \/><\/p>\n<p>This supply represents another example of how Tempco is able to <strong>develop advanced solutions for industrial cooling<\/strong>, with high efficiency and reduced delivery times. Thanks to our <a href=\"https:\/\/www.tempco.it\/blog\/en\/10296\/compact-thermoregulating-units-for-wide-temperature-range-in-pharma-labs\/\" target=\"_blank\" rel=\"noopener\">experience in the pharma sector<\/a>, we were able to respond promptly to the customer&#8217;s needs, ensuring a high-performance and ready-to-use system.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Advanced solutions for thermal control in pharmaceutical processes with the supply of two chillers operating at temperatures down to -30\u00b0 C to ensure precision cooling of reactors in a new production line.<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[64,61,63,113,473,84],"tags":[4328,112,127,486,126,1240,138,559,4330,4329,148,1923,3832,4327,1619,2506,429,4331,3889,4332],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Chiller at -30\u00b0 C for high precision cooling in pharma production - 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